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Search over 300 published research articles on hypochlorous acid

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Results: 13 published articles

NCBI - Oral Biofilm Bacteria

Effects of stabilized hypochlorous acid on oral biofilm bacteria

Microbe(s): NCBI - Oral Biofilm Bacteria

ABSTRACT - Full Text PDF

Low concentrations of HOCl (5 ppm), stabilized with 0.14% or 2% HAc, significantly reduced viability in multi-species biofilms representing supra- and sub-gingival oral communities, after 5 min, without causing erosion of HA surfaces. No equivalent antimicrobial effect was seen for CHX. Gram-positive and Gram-negative bacteria showed no significant differential suceptibility to stabilized...

NCBI - SARS-CoV-2-surrogate

Hypochlorous acid inactivates oral pathogens and a SARS-CoV-2-surrogate

Microbe(s): NCBI - SARS-CoV-2-surrogate

ABSTRACT - Full Text PDF

HOCl solution (45–60 ppm) is still effective against oral pathogens and SAR-CoV-2 surrogate viruses even in the presence of saliva and after passing through the dental unit water line. This study indicates that the HOCl solution can be used as therapeutic water or mouthwash and may ultimately reduce the risk of airborne infection in dental...

NCIB - Infectious Pathogens

The Effect of Hypochlorous Acid Disinfectant on the Reproduction of Details and Surface Hardness of Type III Dental Stone

Microbe(s): NCIB - Infectious Pathogens

ABSTRACT - Full Text PDF

A total of 100 samples of type III dental stone, 50 samples for each test, which include the reproduction of detail test and surface hardness test, were prepared and randomly divided into five groups, 10 samples for each test group, which include group A (control), group B (immersion in 200 ppm HOCl disinfectant for five minutes), group C (spraying with 200 ppm HOCl disinfectant for five...

BioMed Research International - Covid 19

Environmental Disinfection of a Dental Clinic during the Covid-19 Pandemic: A Narrative Insight

Microbe(s): BioMed Research International - Covid 19

ABSTRACT - Full Text PDF

Surface disinfection via aerosol (SDVA). The device produces dry fog through a turbine at high speed that atomized and sprays disinfectant. Usually, H2O2 and hypochlorous acid (HOCl) are used as a disinfectant (Figures 1 and 2). The disinfectant is atomized into ultrafine droplets, blown into the air, and, after 10-30 min, settles on all surfaces; these disinfectant droplets quickly begin to...

American Association of Oral and Maxillofacial Surgeons - COVID-19

COVID-19 (Coronavirus Disease 2019) Virus Structure and Mechanism of Infection

Microbe(s): American Association of Oral and Maxillofacial Surgeons - COVID-19

ABSTRACT - Full Text PDF

On contact with the virus, a disinfectant agent changes the protective protein coat, which loses its structure and aggregates, forming clumps of proteins with other viruses.9,10 Currently, the US Environmental Protection Agency has recommended numerous disinfectants against COVID-19 including hypochlorous acid (HOCl).11 The mechanism of disinfection involves the destroying of the cell wall of...

Brazilian Dental Journal

Viability and Effects on Bacterial Proteins on Dental Oral Rinses with Hypochlorous Acid as Active Ingredient

Microbe(s): Brazilian Dental Journal

ABSTRACT - Full Text PDF

Hypochlorous acid rinses are proposed for plaque control and as a wound healing agent for its use in oral health, due to its low toxicity, high antimicrobial efficacy, anti-inflammatory effect, induction to cell proliferation and its background as a topical solution in the antisepsis of wounds in clinical medicine 16. HOCl has also the ability to oxidize the amino acid taurine and induce the...

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 87.1 (1999): 83-87

Bactericidal effect of electrolyzed neutral water on bacteria isolated from infected root canals

Microbe(s): Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 87.1 (1999): 83-87

ABSTRACT - Full Text PDF

Objective. The purposes of this study were to examine the time-related changes in pH, oxidation-reduction potential, and concentration of chlorine of electrolyzed neutral water and to evaluate the bactericidal effect of electrolyzed neutral water against bacteria from infected root canals. Study Design. Various properties of electrolyzed neutral water pH value, oxidation-reduction potential, and...

Dental materials journal 21.2 (2002): 93-104

Durability of bactericidal activity in electrolyzed neutral water by storage

Microbe(s): Dental materials journal 21.2 (2002): 93-104

ABSTRACT - Full Text PDF

Electrolyzed strong and weak acid waters have been widely used for sterilization in clinical dentistry because of their excellent bactericidal activities. Electrolyzed neutral water was recently developed with a new concept of long-term good durability in addition to the excellent bactericidal activity similar to acid waters. The present study, evaluated the storage life of this water compared...

JOURNAL OF MICROBIOLOGY-SEOUL- 44.4 (2006): 417

Antibacterial effect of electrolyzed water on oral bacteria

Microbe(s): JOURNAL OF MICROBIOLOGY-SEOUL- 44.4 (2006): 417

ABSTRACT - Full Text PDF

This study investigated the antibacterial effect of electrolyzed water on oral bacteria both in vitro and in vivo. Tap water was electrolyzed in a water vessel using platinum cell technology. The electrolyzed tap water (called Puri-water) was put in contact with five major periodontopathogens or toothbrushes contaminated with these bacteria for 30 sec. In addition, Puri-water was used as a...

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 107.2 (2009): 295-298

Antimicrobial efficacy of 4.2% sodium hypochlorite adjusted to pH 12, 7.5, and 6.5 in infected human root canals

Microbe(s): Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 107.2 (2009): 295-298

ABSTRACT - Full Text PDF

Objective: The purpose of this study was to determine the antimicrobial efficacy of sodium hypochlorite adjusted to pH 12, 7.5, and 6.5 in human root canals infected by Enterococcus faecalis. Study design: One hundred sixty-five human single-rooted teeth were prepared and inoculated with E. faecalis for 48 h. Teeth were divided into 3 experimental groups according to the irrigation pattern used:...

Journal of Endodontics 42.7 (2016): 1120-1125

Bactericidal Effect of Strong Acid Electrolyzed Water against Flow Enterococcus faecalis Biofilms

Microbe(s): Journal of Endodontics 42.7 (2016): 1120-1125

ABSTRACT - Full Text PDF

Introduction This study evaluated the bactericidal effect of strong acid electrolyzed water (SAEW) against flow Enterococcus faecalis biofilm and its potential application as a root canal irrigant. Methods Flow E. faecalis biofilms were generated under a constant shear flow in a microfluidic system. For comparison, static E. faecalis biofilms were generated under a static condition on coverslip...

International Journal of Molecular Sciences 17.7 (2016): 1161

Effectiveness of hypochlorous acid to reduce the biofilms on titanium alloy surfaces in vitro

Microbe(s): International Journal of Molecular Sciences 17.7 (2016): 1161

ABSTRACT - Full Text PDF

Chemotherapeutic agents have been used as an adjunct to mechanical debridement for peri-implantitis treatment. The present in vitro study evaluated and compared the effectiveness of hypochlorous acid (HOCl), sodium hypochlorite (NaOCl), and chlorhexidine (CHX) at eliminating Gram-negative (E. coli and P. gingivalis) and Gram-positive (E. faecalis and S. sanguinis) bacteria. The effect of...